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They act as chemical messengers in the body and play a key role in many processes

mild up, FC is between 0 and 2 and adjusted P value is less than 0.05

27 Point mutations in the DNA gyrase or topoisomerase IV genes confer fluoroquinolone resistance

These mainly involve the inhibition of the master regulator MITF, resulting from the reduction of intracellular cAMP levels, increases in cytoplasmic -catenin and/or the activation of ERK signaling

Alanbaei M, Abu-Farha M, Hebbar P, Melhem M, Chandy BS, Anoop E, Cherian P, Al-Khairi I, Alkayal F, Al-Mulla F et al

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