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Carnitine can effectively inhibit mitochondria-dependent apoptosis by regulating the balance of Bcl-2/Bax, inhibiting the mitochondrial permeability transition (MPT), and reducing mitochondrial membrane damage and the release of apoptosis-related factors [14, 15]

doi:10.1016/j.diabres.2008.12.018 [DOI] [PubMed] [Google Scholar] 62.Hearn L, Derry S, Moore RA

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Description GNC Acetyl-L-Carnitine alpha-Lipoic Acid 500mg/200 mg Provides 500mg Acetyl-L-Carnitine, and 200mg alpha-Lipoic Acid per serving Supports positive mood balance and antioxidant regeneration.* Gluten free, no sugar, no artifical flavors, sodium free, no wheat, no dairy 60 caplets per container Key Features: Supports positive mood balance and antioxidant regeneration.* Gluten free, no sugar, no artifical flavors, sodium free, no wheat, no dairy 60 caplets per container Country of Origin: United States of America Manufacturer/Importer/Packed By: GNC

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Even high doses have not resulted in improved carnitine concentrations in muscle and no change in function