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However, because B12 bound to haptocorrin is not metabolically active, use of only total serum B12 may result in Black patients being incorrectly identified as having a high B12 status

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Memorial Sloan Kettering Cancer Center

The therapys success is checked by looking at clinical markers

Modern processed foods, including fortified breakfast cereal , often contain synthetic cyanocobalamin that requires extensive conversion processes to become bioactive methylcobalamin

Pather S, Madhi SA, Cowling BJ, Moss P, Kamil JP, Ciesek S, Muik A, Treci