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Because anaphylaxis is a life-threatening emergency, there are no absolute contraindications to epinephrine administration

Activating both at the same time produces a substantially larger pulse more than the sum of the two individual effects
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(accessed 4 May 2017) Claridge LC, Eksteen B, Smith A, Shah T, Holt AP (2010) Acute liver failure after administration of paracetamol at the maximum recommended daily dose in adults

Conservative vs surgical: Some tendon injuries managed conservatively (physical therapy, activity modification) versus surgery

Yeah, people do that in black belt
