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While pharmacological interventions remain central to managing HU, persistent challenges such as treatment resistance necessitate the exploration of novel drug targets and lifestyle modifications

IL-1, while following a similar downward trend, did not exhibit consistent differences between groups across time points

doi: 10.1105/tpc.106.046953

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[DOI] [PMC free article] [PubMed] [Google Scholar] 152.Kranzer K., Elamin W.F., Cox H., Seddon J.A., Ford N., Drobniewski F

other antioxidantsprevents the potential negative consequences of excessive antioxidant supplementation, which can paradoxically impair adaptations to exercise and normal immune function