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The etiopathogenesis of FM is thought to involve complex interactions between genetic predisposition and environmental and biological factors, with central sensitization playing an important role [1, 5]

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Support for clinical trials participation in the last five years has been received from Biogen, Alexion, Orion Pharma, WAVE, the EU Horizon 2020 programme and UK NIHR

Zhang Q, Hu Y, Hu JE, Ding Y, Shen Y, Xu H, et al

SAMe is the universal methyl donor

Connecting metabolic rewiring with phenotype switching in melanoma
