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Chin J Biol Control 23(1):68 Zhu Y-G, Pilon-Smits EA, Zhao F-J, Williams PN, Meharg AA (2009) Selenium in higher plants: understanding mechanisms for biofortification and phytoremediation

Notably, susceptibility to stress increases with age via up-regulation of the NADPH oxidase in the hippocampus (99)

These three actives have indeed shown that they are capable of improving microcirculation, via different mechanisms: caffeine accelerates blood circulation, vitamin K strengthens vascular walls, thus promoting lymphatic drainage and microcirculation, and immortelle essential oil inhibits the synthesis of nitric oxide, a compound contributing to fluid stagnation

These ingredients are considered lipotropic agents, or fat-burning nutrients, which may support the metabolism of fat

Key actions: Regulates melanin production Helps fade dark spots Improves skin clarity Safe for long-term use under guidance 3