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Additionally, niacin has been noted to increase fasting blood glucose by inducing insulin resistance in some cases

We should mention that no potential bias was occurred in this trial since patient evaluation was performed through the instrumental techniques and standard photography (Skin Color Catch and VisioFace 1000D instruments) and the investigating dermatologist was blinded to the type of preparation assigned to each patient

Uncropped and unprocessed scans of blots are provided in the Source Data file

10.1016/j.ejpb.2024.114513 239

Figure 3 shows the prediction-corrected VPC plots, where most observed data fell within the 95% confidence interval (CI) generated by model simulations, showing that the final model had good forecasting ability

FA (5 mg mL 1 , dissolved in 0.5 M NaHCO 3 , at pH 8) was added and stirred overnight