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The resulting ROS released in the tumour microenvironment impaired the cytotoxic activity of NK cells by oxidising a serine residue in the initiation factor eIF2B, leading to downregulation of NKG2D and its ligands

10.1021/bi0255874

The lack of proper safety/dosing foundational data, Category 2 compounding ban (i.e

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The supernatant contained the RIPA-soluble protein components

In preclinical research, AOD has been associated with increased lipolysis (fat breakdown) and reduced lipogenesis (fat storage)