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In certain areas of the world where G6PD deficiency reaches epidemic proportions and ingestion of fava beans is staple, screening for endemic G6PD-deficient variants and avoiding fava beans in those that are G6PD deficient reduces hospitalizations and RBC transfusions

However, successful lactation is also associated with long-term improvements in maternal metabolism and mitochondrial function, supporting the lactation reset hypothesis, which suggests that these adaptations can confer lasting metabolic benefits if the process is not excessively strained [88]

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doi:10.3389/fnins.2016.00538 [PubMed] Bergen N, Jaddoe V, Timmermans S, et al

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism