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Papademetriou IT, Porter T

The Neurofibromatosis Type 1 Gene Encodes a Protein Related to GAP

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There are great variations in nuclear GSH concentration and its regulation mechanisms during the cell cycle since cells starting the proliferation phase have high levels of nuclear GSH, while resting cells have similar or lower GSH levels in the nucleus than in the cytoplasm (68, 72, 73)

Primary cells derived from five out of 14 patients (35.7%) were successfully maintained beyond passage 5, and long-term cultures were subjected to whole-exome sequencing (WES) (Fig