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Rationale: Elevated GH and IGF-1 support osteoblast proliferation, collagen synthesis, and overall tissue repair capacity

Key proposal requirements are listed below: Key Requirements: Phase I This topic is only accepting Direct to Phase II (DP2) proposals for a cost up to $2,000,000 for a 24-month period of performance

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The bodyweight of all rats was recorded on day 1, 20, 36, and 52
6 , e004078 (2017)

Reactivation of cAMP pathway by PDE4D inhibition represents a novel druggable Axis for overcoming tamoxifen resistance in ER-positive breast cancer
