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However, chronic administration of 16 g oral pyridoxine per day for 1240 months can cause: severe and progressive sensory neuropathy characterized by ataxia (loss of control of bodily movements) which is dose dependent, and the symptoms usually stop if the patient discontinues the pyridoxine supplements as soon as the neurologic symptoms appear painful, disfiguring dermatological lesions photosensitivity gastrointestinal symptoms, such as nausea and heartburn Drug Interactions Vitamin B6 can interact with: Cycloserine: (Seromycin) is a broad-spectrum antibiotic used to treat tuberculosis

Another issue is pain

I use 26g 1 inch needles to inject and use a separate larger needle to draw up liquid from ampoules I couldn't get from usual pharmacy so purchased from here

NICE guidance recommends 1 mg hydroxocobalamin three times weekly for 2 weeks for patients without neurological symptoms, with lifelong maintenance therapy for irreversible causes

Following these handling practices helps maintain the chemical stability and reproducibility required for reliable experimental use

Choline, like inositol, enables the liver to get rid of waste and prevents the deposition of cholesterol in the body