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Description
Symmetric dimethylarginine (SDMA) is a small molecule that comes from the natural breakdown of proteins in the body

Although chemopreventive effects were identified through epidemiological evidence, chemical carcinogenesis models and transgenic mouse models, more extensive mechanistic studies were performed to evaluate its therapeutic potential in various pre-clinical models

After treatment with CPP-CAND, a significant reduction of approximately 7.1-fold in the number of FOXO4 foci was observed in the nuclei of the senescent cells

Regul Toxicol Pharmacol 152:105681

G., Arul, V., Kumar, M

Finkey, and S
