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In contrast, no such translocation could be detected in morphine-treated cells which produce a PKC-dependent MOR desensitization

has also shown, in a clinical study, that patients with mild to moderate dementia manifested improved cognitive ability

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Quantitative structureactivity relationship (QSAR) studies Traditional QSAR-based methods are very common in early drug design and prior to discovering new lead compounds or for use in drug repurposing to predict the relationships between the structural properties of chemical compounds and biological activities, thus helping in ligand-based drug design [27]

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