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NNMT is a cytosolic enzyme that is primarily expressed in the liver and catalyzes the transfer of methyl group from the cofactor S-(5-adenosyl)-L-methionine (SAM) to other substrates

Overall scale weight may not change dramatically because lean muscle mass tends to increase alongside fat reduction

Despite the progress in understanding NNMT functions, knowledge gaps remain

Research findings are preliminary and do not imply safety or efficacy.

Methylcobalamin cannot be made by plants or by animals