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Glucose-dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight-loss action of GLP-1R agonism

, Rabbani N., and Thornalley P

Tennen RI, Michishita KE, Chua KF

Under the surface, youre dealing with two completely different systems: one that controls how much energy your cells can produce , and another that controls how well your body can repair and regenerate

The secretion of growth factors such as hepatocyte growth factor (HGF) and interleukin-10 (IL-10) by MSCs plays a critical role in modulating the inflammatory response, promoting angiogenesis, and recruiting endogenous progenitor cells to the site of injury

Peptides that reduce gut inflammation effectively change the messages traveling up the vagus nerve from alarm signals to calm-state signals