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Lee SK, Sirajudeen KN, Sundaram A, Zakaria R, Singh HJ

Large-scale, well-designed trials with proper randomization and blinding are needed to determine whether high-dose oral supplementation is as effective as intramuscular injection for increasing vitamin B 12 status and alleviating clinical symptoms of vitamin B 12 deficiency

It converts dietary choline to betaine

Epimutations at two separate loci impose mitochondrial dysfunction in wild-type cells

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