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Nanoparticles in oral health care: clinical insights and future perspectives, Applications of Multifunctional Nanomaterials

Active targeting of dendrimers induces P-glycoprotein (P-gp) overexpression and apoptosis in multidrug-resistant cells (207)

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The most common included: Injection-site irritation or redness Water retention and swelling Elevated blood pressure Headaches or dizziness Digestive discomfort such as diarrhoea During Phase II clinical trials, three subjects experienced heart attacks after CJC-1295 administration (Teichman et al., 2005)