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Proceedings of the National Academy of Sciences of the United States of America, 110(24), E2153E2162

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NAD + is a vital coenzyme in fuel metabolism and the transformation of carbohydrate into lipid ( + utilization indicates that elevated NNMT expression may inhibit energy expenditure and promote fat deposition by limiting NAD + -dependent processes (Trammell and Brenner, 2015)

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The itch in eczema is not primarily histamine-mediated, which is why antihistamines generally provide poor relief