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One is that every lab determines its own reference ranges

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Normally, Nrf2 is sequestered in the cytoplasm by Keap1 (Kelch-like ECH-associated protein 1), a protein that also acts as an adaptor protein for the Cullin 3-dependent E3 ubiquitin ligase to mediate the ubiquitination and degradation of Nrf2

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The NS injections were given S.C to the control group once a day for 4 consecutive days

Our unpublished studies, as well as research results from other laboratories, indicate that minocycline, a tetracycline antibiotic, a microglia inhibitor and a MMP9 blocker, alleviates the development and symptoms of CIPN caused by oxaliplatin, cisplatin, paclitaxel and bortezomib [144,145,146,147,148]