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10.1126/scitranslmed.abl4414 [DOI] [PMC free article] [PubMed] [Google Scholar] 319.Okura, N

The formation of urinary calculi is a complex process, which includes urinary supersaturation, crystal nucleation, crystal growth and aggregation, and crystal attachment to renal tubular epithelial cells (3)

Nanoparticles increase the therapeutic effect by facilitating the delivery of the drug to the target tissue, thereby improving the deposition of the drug in the lungs (Yang et al., 2019)

The safety concern is not about toxicity

Combined with physical therapy, they reported faster recovery and reduced pain within one month

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