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(7) as some patients with a history of OUD who are currently sober need opioids for treatment of acute or chronic pain syndromes, L-NACme, if it attenuates euphoria and physical dependence, could be added to opioid analgesics when given to people with a history of OUD, thereby eliminating the risk of opioid analgesics precipitating euphoria, drug cravings and their substantially increased risk of relapse
Li FJ, Long HZ, Zhou ZW, Luo HY, Xu SG, Gao LC

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Stahel et al., 2001

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Inflammation is essential to combat infection
