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In preclinical studies, it inhibited proliferation of a broad range of tumor cell lines (cell IC50 6.2 nM to 4.3 M) and inhibited HUVEC growth in response to HGF and VEGF as an in vitro model of angiogenesis [116]

An increase in ROS can lead to hypomethylation of sperm DNA, which can reduce spermatogenesis and precipitate the development of testicular cancer [54]

10.1007/s12011-014-0218-y Biol

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Its role in research is limited to analytical, comparative, and observational study conducted within structured investigational environments