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Sudlow C, Gallacher J, Allen N, Beral V, Burton P, Danesh J, et al

In clinical trials, lycopene has demonstrated anti-atherogenic effects such as improvement in lipid profiles, blood pressure, and endothelial function, and reduction of inflammation and oxidative stress

Jul 2012;26(4):155-66

Reduced serum free carnitine as well as reduced levels of 3-keto-VPA, the main metabolite of -oxidation of VPA, was first reported in 1982 by Bohles and coworkers [53] in a 3-year-old girl who developed acute liver disease with typical features of Reye's syndrome after treatment with VPA for 6 months