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doi:10.1378/chest.12-2357 Santus P, Corsico A, Solidoro P, Braido F, Di Marco F, Scichilone N

Macrophages detect these apoptotic cells using specific efferocytic receptors, such as Mer tyrosine kinase (MERTK) and T-cell immunoglobulin and mucin domain containing-4 (TIM-4), which recognize PS directly or indirectly through bridging molecules like Growth Arrest-specific gene 6 (Gas6) and Protein S [24, 30]

Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species

Weakened Immune Function Improves immune resilience by enhancing cellular repair and bolstering antioxidant defenses critical to immune activity

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Moreover, these findings were in compliance with previous studies, where L