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10.3389/fmars.2022.884897

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Thus, NCOA4 is recognized as a facilitator of ferroptosis, while HERC2 (an E3 ubiquitin ligase for NCOA4 and FBXL5), VAMP8 (involved in autophagosome-lysosome fusion), and C-MYC have the potential to influence ferritin autophagy by modulating NCOA4 expression

doi: 10.2147/IDR.S256773 169 LinaniA.BenarousK.Bou-SalahL.YousfiM.Goumri-SaidS

Altered kynurenine metabolism correlates with infarct volume in stroke

Although the expressivity of NF-1 varies considerably, even among individuals in the same family who are genotypically identical, the disorder is considered to be 100% penetrant