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36,49 The latest research indicates that TMAO can impair -cell function and glucose tolerance, and the mechanism may be related to the promotion of -cell ERS, dedifferentiation, and apoptosis

Les groupes risque comprennent galement les femmes enceintes, les personnes ges, les personnes atteintes de pancratite et de diabte sucr de type 2

Abramovitz M, Homma H, Ishigaki S, Tansey F, Cammer W, Listowsky I: Characterization and localization of glutathione-S-transferases in rat brain and binding of hormones, neurotransmitters, and drugs

ROS also interact with unsaturated fatty acids in phospholipids, and aldehydes such as 4-hydroxynonenal, 4-hydroxyhexanal, acrolein, and MDA are the most reactive compounds (169)

In addition, dose-dependent kinetics have been reported by some, while others have claimed that this interpretation arises from artifacts of insensitive detection methods [37, 7577]

, 3, 6 12 (DAS 28), HAQ (Health Assessment Questionnaire), (SF-36),
