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The interval between the positively charged quaternary nitrogen of phosphocholine and the acidic sidechain of Glu81 is 3.8 , indicating that this interaction is a critical determinant of phosphocholine binding [34]

Similarly, weakened CD4+ T cell responses impair CD8+ T cell priming and antibody formation, allowing viral persistence and expanding the quasispecies reservoir for RAS emergence [195]

Testing and Counseling Testing The optimal method of detecting HCV infection is to screen populations for history of risk, and to test selected individuals with an identifiable risk factor

Factors affecting results Several variables influence treatment outcomes