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Journal of Biomaterials Science, Polymer Edition, 20(12):15371552

Methylation of PRDX3 expression alleviate ferroptosis and oxidative stress in patients with osteoarthritis cartilage injury

In PD, misfolded syn and neuronal damageassociated molecules (e.g., ATP, HMGB1) activate microglia through pattern recognition receptors including TLR2 and TLR4 [14], triggering a proinflammatory phenotype with cytokines (TNF and IL1) and ROS release [15]

Basye JL