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This process is vital for effective fat burning, especially during exercise or calorie-restricted diets, supporting both weight management and reduced fatigue

Knockdown of CrAT or CrOT significantly decreased glucose-derived acetyl-CoA to around 50% of the level in controls (Extended Data Fig

Longo N, Di Amat C, Pasquali M (2006) Disorders of carnitine transport and the carnitine cycle

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13 CarronM.VeroneseS.GomieroW.FolettoM.NittiD.OriC.et al (2012)

The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status