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& Hegele, R

Signaling Pathway Activation via G-Protein and Phospholipase C This diagram illustrates a signaling pathway in which a messenger molecule binds to a receptor on the cell membrane, activating an associated G-protein

Metabol Open 25:100342

Proceedings of the National Academy of Sciences of the United States of America, 104 (9), 32313236

Its also rampant in the world of creatine too

The alleviation of THO, as well as the depletion of NK/NKT cells, significantly reduced the presence of activated DCs in the inflamed eyes of DED mice, alleviated their antigen-presenting properties, attenuated Th1 and Th17 cell-driven eye inflammation, down-regulated MMP-3 and MMP-9 expression, and reduced apoptosis of their corneal and conjunctival epithelial cells, confirming the important pathogenic role of THO in NK and NKT cell-driven inflammation in the eyes of DED patients [58]