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Advanced glycation end products in foods and a practical guide to their reduction in the diet

The inability of antioxidant systems, such as GPX4-dependent pathways, to counteract ROS amplifies ferroptotic damage (90)

"We know of over 4,000 antioxidants and none of them can work properly without the master antioxidant, which is responsible for recharging and recycling them

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Zhong CC, Zhao T, Hogstrand C, Song CC, Zito E, Tan XY, Xu YC, Song YF, Wei XL, Luo Z

Varghese Alex, P

they frequently lack appropriate specificity, chemical stability, or interference resistance to cellular components [115] and they are mostly incapable of simultaneously quantifying the intricate network of interconnected redox couples (e.g., GSH/GSSG, NAD/NADH, and Trx redox states) with adequate sensitivity under physiologically relevant conditions [116]