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10 NO and its by-products, such as nitrate (NO3-), nitrite (NO2-), peroxynitrite (ONOO-), and 3-nitrotyrosine are called reactive nitrogen species (RNS)

O 2 can reduce ferric iron (Fe 3+ ) to Fe 2+ , which suggests that it can play two roles in producing OH

[DOI] [PubMed] [Google Scholar] 78.Blanco R.A., Ziegler T.R., Carlson B.A., Cheng P.-Y., Park Y., Cotsonis G.A., Accardi C.J., Jones D.P

Glycine Glycine (Gly) is another essential amino acid in the synthesis of GSH

Meanwhile, in non-selenium containing Gpxs, which represent the majority of non-vertebrate Gpxs, the selenocysteine residue at the active site is replaced by a cysteine residue and the enzyme follows Michaelis Menten saturation kinetics (Toppo et al., 2009)

The pathophysiological processes of I/R injuries are both systemic and local and can be divided into two phases