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The safety of TB-500 is inseparable from the context in which it is administered: supervised clinical protocols with pharmaceutical-grade sources produce a fundamentally different risk profile than unsupervised self-administration with research chemicals

Although eugenol is classified as GRAS at low doses, doseresponse relationships and long-term safety profiles in MASLD conditions are not well defined, especially considering reports of hepatotoxicity at high concentrations therefore further research is required to enhance its safety profile [178]

doi:10.1038/emboj.2011.105, PMID: 21478822 Trachootham D, Lu W, Ogasawara MA, Nilsa RD, Huang P (2008) Redox regulation of cell survival

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Chauhan B, Kumar G, Kalam N, et al

Those products have a place in a skincare routine