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Cellular senescence or stemness: Hypoxia flips the coin

It fights those nasty free radicals, helps your liver clean things up, and can even lighten your skin by controlling how much melanin you make

10.1016/j.neubiorev.2021.06.038 128 KoobG

Studies have shown that, in both non-obese diabetic (NOD) mouse models and patients with T1DM, dysregulated arginine metabolism is closely associated with increased macrophage NO production and is linked to pancreatic -cell injury and disease progression ( A similar metabolism-polarization mechanism has also been demonstrated in psoriasis

Physiology of astroglia

[DOI] [PubMed] [Google Scholar] 90.Hmingthansanga V., Singh N., Banerjee S., Manickam S., Velayutham R., Natesan S