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Scott et al, 1992), such as Itga2, Itga3, Itga4, Itga5, ItgaV, Itgb1 , and Itgb3 , which mediate adhesion to collagens and fibronectin (Fig
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This damage triggers genetic mutations that cause uncontrolled growth of these cells
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Chemotherapy is predominantly used in patients with metastatic disease, however, prognosis is very poor, with an estimated 5-year survival rate of only 15%[18,20]
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