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After acclimation for 1 week, all rats were randomly divided into eight groups ( N = 5 per group), including CK group (normal feed (ND)), ABX group (ND + antibiotic cocktails (0.2 g/L metronidazole, 0.1 g/L vancomycin, 0.2 g/L ampicillin, and 0.2 g/L neomycin)), ABX + S-AM-0.6 group (antibiotic cocktails + 0.6 mg/kg of S-amlodipine + ND), ABX + S-AM-1.2 group, ABX + S-AM-5 group, S-AM-0.6 group (0.6 mg/kg of S-amlodipine + ND), S-AM-1.2 group (1.2 mg/kg of S-amlodipine + ND), and S-AM-5 group (5 mg/kg of S-amlodipine + ND), as shown in Figure 1

Limitations of the model This model was designed to allow us to study various regulatory mechanisms in the transsulfuration pathway and the effects of oxidative stress, particularly as applied to Down syndrome and autism

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S-107, S48168 (ARM210)] and troponin activators (e.g

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