melanotic definition Melanocytic Nevus: What Is It, Causes, Signs and Symptoms, and More Oral melanotic macules are harmless
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Other reported effects include flushing, headache, injection-site reactions, and a small transient increase in blood pressure
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They appear during childhood or teen years and develop on the skin's surface (epidermis) or just underneath (dermis)

A previous history of vitiligo can also make a patient more vulnerable to a drug-induced extension of their pigment loss

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