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Induction of necrotic cell death and activation of STING in the tumor microenvironment via cationic silica nanoparticles leading to enhanced antitumor immunity
The emergence of neoplastic alterations adjacent to the central vein in the hepatic tissue of BaP-treated tilapia indicates a possible initiation of hepatocellular carcinoma which is confirmed by inflammatory cell infiltration indicating a persistent cellular injury since BaP could trigger chronic inflammation and carcinogenesis through mutagenic and pro-inflammatory mechanisms (Chenghao Fu et al
[DOI] [PubMed] [Google Scholar] 12.Lauer A.A., Grimm H.S., Apel B., Golobrodska N., Kruse L., Ratanski E., Schulten N., Schwarze L., Slawik T., Sperlich S., et al
With a high prevalence in developed countries and a significant increase in incidence in developing countries, it has grown to become a global burden 1
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