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doi: 10.1136/annrheumdis-2012-202589.

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Endotoxin, Toll-like Receptor-4, and Atherosclerotic Heart Disease

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HSV-2 infection groups were blocked with 5% BSA for 1 h and stained with the HSV-1/2 ICP5 antibody (Santa Cruz, Cat#sc-56989,1:200 dilution) overnight at 4 C, and then incubated with Alexa Fluor 488 donkey anti-mouse IgG (Jackson ImmunoResearch, Cat#AB_2340846, 1:200 dilution) before examination using a thunder DMI8 confocal microscope (Leica)

Rapamycins efficacy is further limited due to its metabolism via cytochrome P450 3A4 (Cyp3A4), which is induced by rifampin, complicating its use alongside standard TB treatments