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Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, et al

Independent domains To ferret out how the mitochondria does it, the researchers used a combination of biochemical studies, computational methods, and genetic screens to discover that SLC25A39 is both a sensor and a transporter at the same time, Birsoy explains

Testing new drugs directly on patients with existing medical conditions could lead to unpredictable complications, making it difficult to determine whether a reaction is caused by the drug or the illness itself

Why We Picked Them: Clinical team

doi: 10.1056/NEJM199909023411004

In the current study, we utilized a transgenic mouse model to elucidate the role of GSH in hepatic responses to chronic ethanol consumption and explored underlying mechanisms