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Description
This manifests as genomic instability through the accumulation of mutagenic lesions like 8-oxoguanine (8-oxoG), which drives both disease risk and progression by acting as an epigenetic-like mark [230, 231]

This is why proper patient selection and dosing are critical

Herv F, Ghinea N, Scherrmann J-M

These stones are especially normal in conditions that increase bilirubin production or alter bile composition

10.1038/s41467-023-43570-y 140 JangH.ArceF

Glycyrrhizin Protects -Irradiated Mice From Gut Bacteria-Associated Infectious Complications by Improving miR-222-Associated Gas5 RNA Reduction in Macrophages of the Bacterial Translocation Site
