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, paracetamol preferentially inhibited brain cyclooxygenases (32)), thereby generalized convulsions, particularly presenting brain tissue's high susceptibility to oxidative stress, leaving the glutathione in the brain defenseless to depletion by paracetamol (4, 5), unless BPC 157 was applied

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Iron death, characterized by oxidative stress due to intracellular Fe2+ accumulation, leading to large amounts of ROS production, ultimately results in cell death (161) and contributes to various cardiovascular diseases including atherosclerosis, I/R injury, HF, myocardial infarction and adriamycin cardiomyopathy (162)