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BRD4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis

Acta Pharm Sin B 2018, 8 (4), 687697

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tumors that are endocrine-dependent slow their proliferation and become more sensitive to chemotherapy, radiotherapy, or PI3K inhibition, as seen in PTEN/PIK3CA-mutant endometrial cancer 370

AIH was diagnosed with the following criteria: (1) patients conformed with 1999 revised International Autoimmune Hepatitis Group score10 and/or (2) 2008 IAIHG simplified AIH score6 and/or (3)histological features indicative of AIH ( Animal Experiments Twenty-four female SPF C57BL/6 mice (6 weeks of age) were purchased from Beijing Animal Study Centre and reared under specific pathogen-free conditions in Animal Centre of the Tianjin Medical University