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An uncontrolled, open-label trial in nine patients with probable Alzheimers disease and related dementias, who were also taking acetylcholinesterase inhibitors, reported that oral supplementation with 600 mg/day of lipoic acid appeared to stabilize cognitive function over a one-year period (101)

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Reactions were performed using the SYBR Green PCR Master Mix kit (Applied Biosystems, USA), according to the manufacturers recommendations

Hence, it is advised to strictly follow clinical practice guidelines and conduct a risk assessment for PN before administering potentially neurotoxic medications to MM patients (Richardson et al., 2012)

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