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Description

However, current senolytic compounds, many of which are cancer drugs, come with downsides

Jul 8 2015

Benefits (Research Focus) Cardiolipin stabilization studied for binding cardiolipin in the inner mitochondrial membrane and organizing electron transport chain supercomplexes ROS reduction investigated for decreased reactive oxygen species leak in oxidative stress and aging models ATP synthesis support explored for preserved mitochondrial respiratory chain efficiency and coupling Cristae architecture examined for preservation of inner membrane structure in ischemia and injury models Cellular resilience research researched for protection in cardiac, skeletal muscle, neuronal, and renal preclinical models What Researchers Look At Mitochondrial membrane potential (m) and ATP synthesis efficiency Cardiolipin oxidation, peroxidation markers, and inner membrane integrity Electron transport chain supercomplex assembly and respiratory chain coupling Cardiac function endpoints in ischemia-reperfusion and heart failure models Skeletal muscle endurance, fatigue resistance, and mitochondrial bioenergetics Quick Specs Form: Lyophilized white powder Net Peptide Content: 50 mg per vial Quantity: 1 vial Appearance: White to off-white lyophilizate Reconstitution: Bacteriostatic or sterile water (added by the end researcher) Purity: 99% by HPLC Identity: MS-verified (per COA) Storage: Protect from light Identity Basics Compound: SS-31 (Elamipretide) Synonyms: Elamipretide