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(Particle Peptides) Regenerative medicine Senescent cells impair tissue regeneration (by occupying space, secreting SASP, promoting fibrosis)

Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility

How it works: Tirzepatide activates both GIP and GLP-1 receptors simultaneously

The microglia receptor protein TREM2 is essential for protective innate immune responses against herpesvirus infection in the brain

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat