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Russo T, Kolisnyk B, Aswathy BS et al (2024) The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons

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Vernon SD, Unger ER, Dimulescu IM, Rajeevan M, Reeves WC

doi: 10.1093/oxfordjournals.alcalc.a045609

For instance, it healed transected muscles and counteracted NSAID toxicity without adverse effects.[24][25] Clinical Trials : A Phase I trial (NCT02637284) confirmed safety and pharmacokinetics in healthy volunteers, with no serious adverse events.[26] Phase II trials for ulcerative colitis showed encouraging results, with BPC-157 promoting remission.[27] A recent trial in inflammatory bowel disease patients reported tolerability and potential benefits.[28] The table below highlights select key studies: While robust, the reliance on animal models underscores the need for more large-scale human trials