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It is an essential antioxidant in the placenta because it reduces oxidative stress by constantly scavenging for free radicals, i.e., maintain the placentas integrity

However, periprosthetic joint infections (PJI) are a leading cause of surgery failure, occurring in 1-2% of cases

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In proteins, irreversible modifications such as carbonylation, nitration and over-oxidation disable enzymes and chaperones, collapsing proteostasis (Korovila et al